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Bending the Curve Trial by Trial
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Randomised comparison of sentinel-node biopsy with routine axillary dissection in breast cancer

N = 516

Population
Patients with primary breast cancer, tumour 2 cm or less in diameter.
Design
Randomised trial, March 1998 to December 1999: sentinel-node biopsy with total axillary dissection versus sentinel-node biopsy followed by axillary dissection only if the sentinel node contained metastases.
Arms
  • Sentinel-node biopsy + axillary dissection (control, n = 257): Sentinel-node biopsy and total axillary dissection
  • Sentinel-node biopsy, dissection if positive (experimental, n = 259): Sentinel-node biopsy followed by axillary dissection only if the sentinel node contained metastases
People
Veronesi U
Primary publication: Veronesi U, Paganelli G, Viale G, Luini A, Zurrida S, Galimberti V, et al. A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer. N Engl J Med. 2003;349(6):546-53. PubMedDOI

Appears in

Sources

  1. Veronesi U, Paganelli G, Viale G, Luini A, Zurrida S, Galimberti V, et al. A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer. N Engl J Med. 2003;349(6):546-53.

    PubMedDOI