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Bending the Curve Trial by Trial
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PLCO

Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial: flexible sigmoidoscopy component

N = 154,900NCT00002540

Population
Men and women aged 55 to 74 years in the United States.
Design
Randomised trial; from 1993 through 2001, men and women aged 55 to 74 were randomly assigned either to screening with flexible sigmoidoscopy, with a repeat screening at 3 or 5 years, or to usual care. The colorectal component of the multi-cancer PLCO trial.
Arms
  • Flexible sigmoidoscopy screening (experimental, n = 77,445): Flexible sigmoidoscopy at baseline with a repeat screening at 3 or 5 years
  • Usual care (control): Usual care, no study screening
People
Schoen RE
Primary publication: Schoen RE, Pinsky PF, Weissfeld JL, Yokochi LA, Church T, Laiyemo AO, et al. Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy. N Engl J Med. 2012;366(25):2345-57. PubMedDOI

Appears in

Sources

  1. Schoen RE, Pinsky PF, Weissfeld JL, Yokochi LA, Church T, Laiyemo AO, et al. Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy. N Engl J Med. 2012;366(25):2345-57.

    PubMedDOI