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Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan

Phase observationalN = 1,320

Population
1,320 patients with thymic epithelial tumours (thymoma, thymic carcinoma and thymic carcinoid) treated 1990-1994
Design
Compilation of the records of 1,320 patients with thymic epithelial tumours treated from 1990 to 1994 in 115 institutes certified as special institutes for general thoracic surgery by the Japanese Association for Chest Surgery. Survival is reported by Masaoka stage and extent of resection. Not randomised; the abstract does not state the analysis methods.
Arms
  • Total resection (experimental): Total resection of the tumour
  • Subtotal resection (control): Subtotal resection of the tumour
  • Inoperable (control): Not operated (inoperable group)
People
Kondo K, senior author Monden Y
Δ 60-month OS+29 pointsΔ 60-month OS+37 points
Show the numbers
Results reported for Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan
EndpointAnalysisTotal resectionSubtotal resection / InoperableEffect
OSStage III and IV thymoma, by extent of resection (group sizes not stated in the abstract)5-year survival rate, as printedfinalKondo 200393% at 5 y64% at 5 yObservational; the groups were not randomised and differ in extent of disease. Roles in this record are formal: the groups are ordered by extent of resection, not by treatment assignment.
OSThymic carcinoma (all stages), by extent of resection (group sizes not stated in the abstract)5-year survival rate, as printedfinalKondo 200367% at 5 y30% at 5 yObservational; the abstract does not give the stages included.
Results reported for Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan
EndpointAnalysisTotal resectionSubtotal resection / InoperableEffect
OSStage III and IV thymoma, by extent of resection (group sizes not stated in the abstract)5-year survival rate, as printedfinalKondo 200393% at 5 y64% at 5 yObservational; the groups were not randomised and differ in extent of disease. Roles in this record are formal: the groups are ordered by extent of resection, not by treatment assignment.
OSThymic carcinoma (all stages), by extent of resection (group sizes not stated in the abstract)5-year survival rate, as printedfinalKondo 200367% at 5 y30% at 5 yObservational; the abstract does not give the stages included.
Primary publication: Kondo K, Monden Y. Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan. Ann Thorac Surg. 2003;76(3):878-84; discussion 884-5. PubMedDOI

Appears in

Sources

  1. Kondo K, Monden Y. Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan. Ann Thorac Surg. 2003;76(3):878-84; discussion 884-5.

    PubMedDOI