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GOG-33

Needs review

Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group Study

Phase observationalN = 621

Population
Patients with Stage I carcinoma of the endometrium (staging as used when the study was done)
Design
Non-randomised Gynecologic Oncology Group surgical-pathologic study of 621 patients with Stage I carcinoma of the endometrium. All were treated with primary surgery consisting of total abdominal hysterectomy, bilateral salpingo-oophorectomy, selective pelvic and paraaortic lymphadenectomy and peritoneal cytology. Surgical-pathologic features were related to extrauterine disease.
Arms
  • Primary surgery with selective lymphadenectomy (experimental): Total abdominal hysterectomy, bilateral salpingo-oophorectomy, selective pelvic and paraaortic lymphadenectomy and peritoneal cytology
People
Creasman WT, Gynecologic Oncology Group
Show the numbers
Results reported for GOG-33
EndpointAnalysisPrimary surgery with selective lymphadenectomyControlEffect
Disease outside the uterus at surgeryPatients with Stage I carcinoma of the endometrium (621)Lymph node metastasis, adnexal disease, intraperitoneal spread and/or malignant cells in peritoneal washingsfinalCreasman 198722%—The abstract gives '144-22%'. The counts as given (144 of 621) would be 23.2%, so the percentage and counts do not agree exactly in the source; the published values are reported as they appear.
Results reported for GOG-33
EndpointAnalysisPrimary surgery with selective lymphadenectomyControlEffect
Disease outside the uterus at surgeryPatients with Stage I carcinoma of the endometrium (621)Lymph node metastasis, adnexal disease, intraperitoneal spread and/or malignant cells in peritoneal washingsfinalCreasman 198722%—The abstract gives '144-22%'. The counts as given (144 of 621) would be 23.2%, so the percentage and counts do not agree exactly in the source; the published values are reported as they appear.
Primary publication: Creasman WT, Morrow CP, Bundy BN, Homesley HD, Graham JE, Heller PB. Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group Study. Cancer. 1987;60(8 Suppl):2035-41. PubMedDOI

Appears in

Sources

  1. Creasman WT, Morrow CP, Bundy BN, Homesley HD, Graham JE, Heller PB. Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group Study. Cancer. 1987;60(8 Suppl):2035-41.

    PubMedDOI