Funen randomised study of screening for colorectal cancer with faecal-occult-blood test
- Population
- People aged 45 to 75 years living on Funen, Denmark in August 1985 (about 140,000 considered).
- Design
- Randomised study on Funen, Denmark; before randomisation, people with colorectal cancer or precursor adenomas and those from a previous pilot study were excluded. Randomisation in blocks of 14 allocated three to screening, three to control and eight not to be enrolled. Hemoccult-II tests with dietary restrictions but without rehydration were sent to the screening group; only people who completed the first round were invited again, for up to five rounds over 10 years, and those with positive tests were offered colonoscopy.
- Primary endpoint
- Colorectal cancer mortality
- Arms
- Screening group (experimental, n = 30,967): Hemoccult-II faecal-occult-blood test every two years, up to five rounds over 10 years, not rehydrated
- Control group (control, n = 30,966): No screening; not told about the study
- People
- Kronborg O