Cis-diamminedichloroplatinum, vinblastine, and bleomycin combination chemotherapy in disseminated testicular cancer
N = 50
- Population
- Patients with disseminated testicular cancer; 3 of 50 were inevaluable because of early death
- Design
- Single-arm series of patients with disseminated testicular cancer treated with cisplatin, vinblastine and bleomycin (PVB). No comparison group. The PubMed abstract does not name the treating centre or the accrual period.
- Arms
- PVB (experimental, n = 50): Cisplatin (cis-diamminedichloroplatinum), vinblastine and bleomycin combination
- People
- Einhorn LH, senior author Donohue J
Show the numbers
| Endpoint | Analysis | PVB | Control | Effect |
|---|---|---|---|---|
| Complete response rateEvaluable patients (50 treated; 3 inevaluable because of early death)Complete remission, as reported by the authors; the abstract does not define it further | finalEinhorn 1977 | 74% | — | The same sentence reports 26% partial remissions. Five patients in partial remission became disease-free after surgical removal of residual disease. The abstract states 3 inevaluable but no evaluable count; the percentages are consistent with 35 of 47 complete remissions and 40 of 47 disease-free (verifier's arithmetic, not a published count). |
| Disease-free status after treatmentEvaluable patients (50 treated; 3 inevaluable because of early death)Overall disease-free status after chemotherapy plus surgical removal of residual disease in 5 patients with partial remission | finalEinhorn 1977 | 85% | — | Follow-up was 6+ to 30+ months at the time of the report; 38 patients were alive and 32 alive and disease-free. |
| Endpoint | Analysis | PVB | Control | Effect |
|---|---|---|---|---|
| Complete response rateEvaluable patients (50 treated; 3 inevaluable because of early death)Complete remission, as reported by the authors; the abstract does not define it further | finalEinhorn 1977 | 74% | — | The same sentence reports 26% partial remissions. Five patients in partial remission became disease-free after surgical removal of residual disease. The abstract states 3 inevaluable but no evaluable count; the percentages are consistent with 35 of 47 complete remissions and 40 of 47 disease-free (verifier's arithmetic, not a published count). |
| Disease-free status after treatmentEvaluable patients (50 treated; 3 inevaluable because of early death)Overall disease-free status after chemotherapy plus surgical removal of residual disease in 5 patients with partial remission | finalEinhorn 1977 | 85% | — | Follow-up was 6+ to 30+ months at the time of the report; 38 patients were alive and 32 alive and disease-free. |