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Bending the Curve Trial by Trial
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Researcher at the Albert Einstein College of Medicine whose laboratory reported in 1979 that taxol promotes microtubule assembly

Susan Band Horwitz

Albert Einstein College of Medicine

Wani and Horwitz write that in 1977 the National Cancer Institute asked Susan Band Horwitz, then at the Albert Einstein College of Medicine, to study how taxol works. Her laboratory published its first paper on the mechanism in 1979, reporting that taxol promoted the assembly of microtubules.

Sources

  1. Wani MC, Horwitz SB. Nature as a remarkable chemist: a personal story of the discovery and development of Taxol. Anticancer Drugs. 2014;25(5):482-7.

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  2. Schiff PB, Fant J, Horwitz SB. Promotion of microtubule assembly in vitro by taxol. Nature. 1979;277(5698):665-7.

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  3. Weaver BA. How Taxol/paclitaxel kills cancer cells. Mol Biol Cell. 2014;25(18):2677-81.

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