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Research student at Aston University who made the first imidazotetrazines in 1979

Robert Stone

Aston University

A 2023 review by Stevens and Wheelhouse says the first imidazotetrazines were synthesised in 1979 by research student Robert Stone at Aston University in Birmingham, and that his laboratory book dated 29 April 1980 records the first synthesis of temozolomide.

Sources

  1. Stevens MFG, Wheelhouse RT. Antitumour imidazotetrazines: past, present… and future?. RSC Chem Biol. 2023;4(10):736-741.

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