Skip to content
Bending the Curve Trial by Trial
?

Chemist at Research Triangle Institute, Co-discoverer of camptothecin and taxol, according to a 2004 review

Monroe E. Wall

A 2004 review credits Monroe E. Wall and Mansukh C. Wani of Research Triangle Institute with discovering camptothecin, first isolated and identified from Camptotheca acuminata, and taxol, from Taxus brevifolia. Wall is first author of the 1966 paper on the isolation and structure of camptothecin and of the 1995 Bruce F. Cain Memorial Award lecture on the two compounds.

Sources

  1. Wall ME, Wani MC, Cook CE, Palmer KH, McPhail AT, Sim GA. Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata. Journal of the American Chemical Society. 1966;88(16):3888-3890.

    DOI

  2. Wall ME, Wani MC. Camptothecin and taxol: discovery to clinic--thirteenth Bruce F. Cain Memorial Award Lecture. Cancer Res. 1995;55(4):753-60.

    PubMed

  3. Oberlies NH, Kroll DJ. Camptothecin and taxol: historic achievements in natural products research. J Nat Prod. 2004;67(2):129-35.

    PubMedDOI