Researcher on T-cell regulation and CTLA-4 blockade
James P. Allison
University of California, Berkeley (laboratory in the 1990s)
Studied the T-cell protein CTLA-4 at the University of California, Berkeley in the 1990s and developed the idea of blocking it to treat cancer. Last author listed on the 1996 Science paper on enhancement of antitumour immunity by CTLA-4 blockade, and joint recipient with Tasuku Honjo of the 2018 Nobel Prize in Physiology or Medicine.