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Bending the Curve Trial by Trial
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Investigator of the St Jude Total Therapy studies

Donald Pinkel

St. Jude Children's Research Hospital

Author of the 1971 JAMA report on the five-year follow-up of "total therapy" for childhood lymphocytic leukemia, and last-listed author of the 1971 Blood report on central nervous system therapy with combination chemotherapy. A 2013 review credits Pinkel and colleagues at the newly opened St. Jude Children's Research Hospital with starting the total therapy approach in 1962. Publisher records list his affiliation as St. Jude Children's Research Hospital and the University of Tennessee.

Milestones

Sources

  1. Pui CH, Evans WE. A 50-year journey to cure childhood acute lymphoblastic leukemia. Semin Hematol. 2013;50(3):185-96.

    PubMedDOI

  2. Pinkel D. Five-year follow-up of "total therapy" of childhood lymphocytic leukemia. JAMA. 1971;216(4):648-52.

    PubMedDOI

  3. Aur RJ, Simone J, Hustu HO, Walters T, Borella L, Pratt C, et al. Central nervous system therapy and combination chemotherapy of childhood lymphocytic leukemia. Blood. 1971;37(3):272-81.

    PubMedDOI

  4. Pinkel D, Simone J, Hustu HO, Aur RJ. Nine years' experience with "total therapy" of childhood acute lymphocytic leukemia. Pediatrics. 1972;50(2):246-51.

    PubMedDOI